Bogen-group. Institute of Immunology, Rikshospitalet and University of Oslo

 
     

The Medical Faculty, University of Oslo   Institute of Immunology       Faculty Division Rikshospitalet

Bjarne Bogen, Professor

 Telephone: +47 23073015

E-mail: b.bogen@labmed.uio.no

FAX: +47 23 073510 /

+47 23 073822

 

Some scientific contributions

1. Id-specific T cells clones and recognition of Id-peptides on MHC class II molecules (Bogen et al. Eur J. Immunol -86a,b, Bogen & Lambris, EMBO-J 89, Snodgrass et al, Eur. J. Immunol. 1992)

2. B cells process their own Ig (Weiss & Bogen PNAS -89, Munthe et al. Eur. J. Immunol -99)

3. Endogenous Ig is antigen processed in ER/Golgi(Weiss & Bogen, Cell -91)

4. Establishment of Id-specific TCR-transgenic mice (Bogen et al., Eur. J. Immunol. -92) and Ig L-chain Id+ mice (Bogen and Weiss, Eur. J. Immunol. -91)

5. Clonal deletion of Id-specific thymocytes (Bogen et al., EMBO-J -93,)

6. Id-specific T cells in B cell tumor protection (Lauritzsen et al., PNAS -94, Bogen et al. Eur. J. Immunol -95, Corthay et al. Immunity 2005).

7. Id+ tumors induce deletion of peripheral Id-specific T cells (Bogen Eur.J.Immunol -96) and Id-specific thymocytes (Lauritzsen et al. Int.J.Cancer -98)

8. Dendritic cells in tumors are spontaneously Id-primed (Dembic et al. PNAS-2000, Dembic et al. Blood -2001).

9. Development as Troy-bodies as vaccines (Lunde et al. Nature Biotechnol -99, McAdam et al., J.Exp.Med. -2001, Rasmussen et al., PNAS -2001, Lunde et al J. Immunol 2002, Schjetne et al, J. Immunol 2003, Schjetne et al, Eur J. Immunol 2005)

10. Development of Vaccibodies as vaccines (Fredriksen et al, Mol. Therapy 2006.

11. Unlinked Id-specific T-B cooperation results in autoimmunity (Munthe et al, J. Immunol. 2004,5, Holmoy et al Eur. J. Immunol 2006)